Identification of conserved, primary sequence motifs that direct retrovirus RNA fate
نویسندگان
چکیده
منابع مشابه
Identification of motifs that significantly associate with antisense sequence activity
Antisense oligonucleotides are able to modulate gene expression levels by a posttranscriptional mechanism involving an RNA:DNA heteroduplex and the cleavage of the RNA by RNase H (1,2). This sequence-specific hybridization between an antisense molecule and its target can, in principle, allow the inhibition of any target mRNA without affecting closely related genes. One approach for identifying ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2018
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gky369